3D printing of functional organoids using viscoelastic capsules
Towards the stable room temperature printing of organoid-forming stem cells
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Module 3. Bio-interfaces across scales
Interfaces between living and synthetic materials often determine the fate and function of engineered biological materials. During Phases 1 and 2 (2014-2022), Module 3 focused on developing a range of materials to direct cell growth and tissue differentiation, induce or inhibit specific cell responses, sense biomarkers in complex and diluted environments, and inhibit viral infections, among others. In Phase 3 (2022-2026), Module 3 has become a multidisciplinary research program involving research groups from all former topical modules. Under the common theme of “Bio-interfaces across scales”, the current projects seek diverse goals, including the development of scaffolds that enable guided tissue growth, the 3D printing of cm-sized organoids at room temperature, the understanding of the molecular mechanisms promoting or antagonizing dispersion stability of protein systems, the introduction of novel antiviral and antimicrobial surfaces and the design of DNA-Origami-based nanosensors for cancer diagnostics.
