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Bioinspired Materials NCCR
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Module 1: Mechanically responsive materials
Research
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Module 1: Mechanically responsive materials
Module 2: Photonic materials
Module 3: Bio-interfaces across scales
Translation projects
Other research projects
Research stories
Publications & Datasets
Datasets
Good scientific practices
Completed projects
Module 1: Mechanically responsive materials
Module 2: Responsive materials by self-assembly
Module 3: Interactions of responsive materials with cells
Module 4: Dynamics of interacting cell-material systems
Other projects
Open Science
Open Access
Open Research Data
Copyright and licenses
Controlled activation of cancer-associated immune cells by stimuli-responsive nanoparticles
Active between 01.06.2014 and 31.05.2018
Main investigator
BOURQUIN Carole
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Involved people
CEREGHETTI Alessandra
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HOCEVAR Sandra
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MASSARAS Aristea
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MOTTAS Inès
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WAGNER Julia
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Related publications
TLR7-based cancer immunotherapy decreases intratumoral myeloid-derived suppressor cells and blocks their immunosuppressive function
Spinetti Thibaud, Spagnuolo Lorenzo, Mottas Inès, Secondini Chiara, Treinies Marina, Rüegg Curzio, Hotz Christian, Bourquin Carole
OncoImmunology
(2016)
Neonatal immune tolerance induction to allow long-term studies with an immunogenic therapeutic monoclonal antibody in mice
Piccand Matthieu, Bessa Juliana, Schick Eginhard, Senn Claudia, Bourquin Carole, Richter Wolfgang F.
The AAPS Journal
(2015)
Mycoplasma hyorhinis-contaminated cell lines activate primary innate immune cells via a protease-sensitive factor
Heidegger Simon, Jarosch Alexander, Schmickl Martina, Endres Stefan, Bourquin Carole, Hotz Christian
PLOS ONE
(2015)
Suppression of intratumoral CCL22 by type I interferon inhibits migration of regulatory T cells and blocks cancer progression
Anz D., Rapp M., Eiber S., Koelzer V. H., Thaler R., Haubner S., Knott M., Nagel S., Golic M., Wiedemann G. M., Bauernfeind F., Wurzenberger C., Hornung V., Scholz C., Mayr D., Rothenfusser S., Endres S., Bourquin C.
Cancer Research
(2015)
TLR and RLR signaling are reprogrammed in opposite directions after detection of viral infection
Hotz Christian, Roetzer Laurin C., Huber Thomas, Sailer Andreas, Oberson Anne, Treinies Marina, Heidegger Simon, Herbst Tina, Endres Stefan, Bourquin Carole
The Journal of Immunology
(2015)
Reprogramming of TLR7 signaling enhances antitumor NK and cytotoxic T cell responses
Hotz Christian, Treinies Marina, Mottas Ines, Rötzer Laurin C., Oberson Anne, Spagnuolo Lorenzo, Perdicchio Maurizio, Spinetti Thibaud, Herbst Tina, Bourquin Carole
OncoImmunology
(2016)
Immune response to functionalized mesoporous silica nanoparticles for targeted drug delivery
Heidegger Simon, Gößl Dorothée, Schmidt Alexandra, Niedermayer Stefan, Argyo Christian, Endres Stefan, Bein Thomas, Bourquin Carole
Nanoscale
(2016)
A rapid screening method to evaluate the impact of nanoparticles on macrophages
Mottas Inès, Milosevic Ana, Petri-Fink Alke, Rothen-Rutishauser Barbara, Bourquin Carole
Nanoscale
(2017)
CCL22 controls immunity by promoting regulatory T cell communication with dendritic cells in lymph nodes
Rapp Moritz, Wintergerst Maximilian W.M., Kunz Wolfgang G., Vetter Viola K., Knott Max M.L., Lisowski Dominik, Haubner Sascha, Moder Stefan, Thaler Raffael, Eiber Stephan, Meyer Bastian, Röhrle Natascha, Piseddu Ignazio, Grassmann Simon, Layritz Patrick, Kühnemuth Benjamin, Stutte Susanne, Bourquin Carole, von Andrian Ulrich H., Endres Stefan, Anz David
The Journal of Experimental Medicine
(2019)
Development of resiquimod-loaded modified PLA-based nanoparticles for cancer immunotherapy: A kinetic study
Thauvin Cédric, Widmer Jérôme, Mottas Inès, Hocevar Sandra, Allémann Eric, Bourquin Carole, Delie Florence
European Journal of Pharmaceutics and Biopharmaceutics
(2019)
Polymer-coated gold nanospheres do not impair the innate immune function of human B lymphocytes in vitro
Hočevar Sandra, Milošević Ana, Rodriguez-Lorenzo Laura, Ackermann-Hirschi Liliane, Mottas Ines, Petri-Fink Alke, Rothen-Rutishauser Barbara, Bourquin Carole, Clift Martin James David
ACS Nano
(2019)
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